About the content
Children with cancer are highly vulnerable to serious infections, making fever a potential emergency. Early recognition and rapid response are critical. This module gives healthcare professionals the tools to assess and manage febrile pediatric oncology patients with precision. Due to their immunocompromised state, these patients are at high risk for life-threatening bacterial infections. A structured clinical approach ensures timely treatment, lowers risk, and improves outcomes. In just 20 minutes, this module will enhance your ability to evaluate and care for febrile pediatric oncology patients—supporting safer, faster interventions when it matters most.
What You Will Learn
- Identify the risk factors that increase susceptibility to invasive bacterial infections in pediatric oncology patients
- Understand the essential steps in the initial evaluation of febrile pediatric patients with an oncologic diagnosis
- Review evidence-based management strategies for treating fever in immunocompromised children
Acknowledgements
Created by
Children’s Hospital of Philadelphia
chop.edu

and
Pediatric Pandemic Network

The Pediatric Pandemic Network is supported in part by the Health Resources and Services Administration (HRSA) of the U.S. Department of Health and Human Services (HHS) as part of cooperative agreements U1IMC43532 and U1IMC45814 with 0 percent financed with nongovernmental sources. The content presented here is that of the authors and does not necessarily represent the official views of, nor an endorsement by HRSA, HHS, or the U.S. Government. For more information, visit HRSA.gov.
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You are free to download and share this work for noncommercial purposes, as long as you credit Children’s Hospital of Philadelphia for the original creation.
Enrollment options
Children with cancer are highly vulnerable to serious infections, making fever a potential emergency. Early recognition and rapid response are critical. This module gives healthcare professionals the tools to assess and manage febrile pediatric oncology patients with precision. Due to their immunocompromised state, these patients are at high risk for life-threatening bacterial infections. A structured clinical approach ensures timely treatment, lowers risk, and improves outcomes. In just 20 minutes, this module will enhance your ability to evaluate and care for febrile pediatric oncology patients—supporting safer, faster interventions when it matters most.
What You Will Learn
- Identify the risk factors that increase susceptibility to invasive bacterial infections in pediatric oncology patients
- Understand the essential steps in the initial evaluation of febrile pediatric patients with an oncologic diagnosis
- Review evidence-based management strategies for treating fever in immunocompromised children
